3OOB
Structural and functional insights of directly targeting Pin1 by Epigallocatechin-3-gallate
Summary for 3OOB
Entry DOI | 10.2210/pdb3oob/pdb |
Related | 1F8A 1PIN 2ITK 2Q5A |
Descriptor | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (5 entities in total) |
Functional Keywords | ww domain-like peptidyl prolyl isomerase, phosphorylation-dependent cis/trans isomerase, proteins with pser/pthr-pro motif, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q13526 |
Total number of polymer chains | 1 |
Total formula weight | 20261.31 |
Authors | Urusova, D.V.,Shim, J.-H.,Kim, D.-J.,Jung, S.K.,Zykova, T.A.,Bode, A.M.,Dong, Z. (deposition date: 2010-08-30, release date: 2011-08-17, Last modification date: 2024-02-21) |
Primary citation | Urusova, D.V.,Shim, J.H.,Kim, D.J.,Jung, S.K.,Zykova, T.A.,Carper, A.,Bode, A.M.,Dong, Z. Epigallocatechin-gallate suppresses tumorigenesis by directly targeting Pin1. Cancer Prev Res (Phila), 4:1366-1377, 2011 Cited by PubMed: 21750208DOI: 10.1158/1940-6207.CAPR-11-0301 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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