3OLE
Structures of human pancreatic alpha-amylase in complex with acarviostatin II03
Summary for 3OLE
Entry DOI | 10.2210/pdb3ole/pdb |
Related | 3OLD 3OLG |
Related PRD ID | PRD_900009 PRD_900065 |
Descriptor | Pancreatic alpha-amylase, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, PYROGLUTAMIC ACID, ... (13 entities in total) |
Functional Keywords | glycosylation, hydrolase-hydrolase inhibitor complex, acarviostatin ii03, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space: P04746 |
Total number of polymer chains | 1 |
Total formula weight | 58794.47 |
Authors | |
Primary citation | Qin, X.,Ren, L.,Yang, X.,Bai, F.,Wang, L.,Geng, P.,Bai, G.,Shen, Y. Structures of human pancreatic alpha-amylase in complex with acarviostatins: Implications for drug design against type II diabetes. J.Struct.Biol., 174:196-202, 2011 Cited by PubMed: 21111049DOI: 10.1016/j.jsb.2010.11.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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