3OFS
Dynamic conformations of the CD38-mediated NAD cyclization captured using multi-copy crystallography
Summary for 3OFS
Entry DOI | 10.2210/pdb3ofs/pdb |
Related | 3I9M |
Descriptor | ADP-ribosyl cyclase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (3 entities in total) |
Functional Keywords | cd38, cyclization, hydrolysis, cadpr, adpr, ara-2'f-nad, ara-2'f-adpr, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type II membrane protein: P28907 |
Total number of polymer chains | 6 |
Total formula weight | 181800.06 |
Authors | |
Primary citation | Zhang, H.,Graeff, R.,Chen, Z.,Zhang, L.R.,Zhang, L.H.,Lee, H.C.,Hao, Q. Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal J.Mol.Biol., 405:1070-1078, 2011 Cited by PubMed: 21134381DOI: 10.1016/j.jmb.2010.11.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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