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3OFS

Dynamic conformations of the CD38-mediated NAD cyclization captured using multi-copy crystallography

Summary for 3OFS
Entry DOI10.2210/pdb3ofs/pdb
Related3I9M
DescriptorADP-ribosyl cyclase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (3 entities in total)
Functional Keywordscd38, cyclization, hydrolysis, cadpr, adpr, ara-2'f-nad, ara-2'f-adpr, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type II membrane protein: P28907
Total number of polymer chains6
Total formula weight181800.06
Authors
Zhang, H.,Lee, H.C.,Hao, Q. (deposition date: 2010-08-16, release date: 2010-12-15, Last modification date: 2023-11-01)
Primary citationZhang, H.,Graeff, R.,Chen, Z.,Zhang, L.R.,Zhang, L.H.,Lee, H.C.,Hao, Q.
Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal
J.Mol.Biol., 405:1070-1078, 2011
Cited by
PubMed: 21134381
DOI: 10.1016/j.jmb.2010.11.044
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

数据于2024-03-27公开中

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