Crystal structure of PHF13 in complex with H3K4me3

Summary for 3O7A

DescriptorPHD finger protein 13 variant, H3K4ME3 HISTONE 11MER-PEPTIDE, GLYCEROL, ... (5 entities in total)
Functional Keywordsphf13; zinc finger; phd domain, nuclear protein, structural genomics, structural genomics consortium, sgc, protein binding
Biological sourceHomo sapiens (human)
Cellular locationChromosome . Nucleus  Q92133
Total number of polymer chains2
Total molecular weight7574.6
Bian, C.B.,Lam, R.,Xu, C.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2010-07-30, release date: 2010-10-06, Last modification date: 2016-06-22)
Primary citation
Chung, H.R.,Xu, C.,Fuchs, A.,Mund, A.,Lange, M.,Staege, H.,Schubert, T.,Bian, C.,Dunkel, I.,Eberharter, A.,Regnard, C.,Klinker, H.,Meierhofer, D.,Cozzuto, L.,Winterpacht, A.,Di Croce, L.,Min, J.,Will, H.,Kinkley, S.
PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.
Elife, 5:-, 2016
PubMed: 27223324 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.10607
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2271000MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3o7a
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Molmil generated image of 3o7a
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Molmil generated image of 3o7a
rotated about y axis by 90°