3O6T

Mycobacterium tuberculosis thioredoxin C C40S mutant in Complex with Quinol Inhibitor PMX464

Summary for 3O6T

• Entry DOI: 10.2210/pdb3o6t/pdb
• Related: 2I1U 3NOF
• Descriptor: Thioredoxin, 4-(1,3-benzothiazol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-one, TRIETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: thioredoxin fold, electron transport, electron transport-inhibitor complex, electron transport/inhibitor
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 51528.90

Authors

Hall, G.,Emsley, J. (deposition date: 2010-07-29, release date: 2010-11-10, Last modification date: 2023-11-01)

• Primary citation: Hall, G.,Bradshaw, T.D.,Laughton, C.A.,Stevens, M.F.,Emsley, J.; Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464; Protein Sci., 20:210-215, 2011; PubMed: 20981751; DOI: 10.1002/pro.533

Experimental method

X-RAY DIFFRACTION (2.4 Å)