3NZK
Structure of LpxC from Yersinia enterocolitica Complexed with CHIR090 Inhibitor
Summary for 3NZK
Entry DOI | 10.2210/pdb3nzk/pdb |
Descriptor | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, N-{(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl}-4-{[4-(morpholin-4-ylmethyl)phenyl]ethynyl}benzamide, ZINC ION, ... (5 entities in total) |
Functional Keywords | deacetylase, endotoxin, metal-binding, hydrolase |
Biological source | Yersinia enterocolitica |
Total number of polymer chains | 2 |
Total formula weight | 70903.72 |
Authors | Cole, K.E.,Christianson, D.W. (deposition date: 2010-07-16, release date: 2011-01-05, Last modification date: 2023-09-06) |
Primary citation | Cole, K.E.,Gattis, S.G.,Angell, H.D.,Fierke, C.A.,Christianson, D.W. Structure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090 . Biochemistry, 50:258-262, 2010 Cited by PubMed: 21171638DOI: 10.1021/bi101622a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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