3NYT
X-ray crystal structure of the WlbE (WpbE) aminotransferase from pseudomonas aeruginosa, mutation K185A, in complex with the PLP external aldimine adduct with UDP-3-amino-2-N-acetyl-glucuronic acid, at 1.3 angstrom resolution
Summary for 3NYT
Entry DOI | 10.2210/pdb3nyt/pdb |
Related | 3NYS 3NYU |
Descriptor | Aminotransferase WbpE, (2S,3S,4R,5R,6R)-5-(acetylamino)-6-{[(R)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3-hydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}tetrahydro-2H-pyran-2-carboxylic acid (non-preferred name), SODIUM ION, ... (4 entities in total) |
Functional Keywords | aminotransferase, plp binding, nucleotide-sugar binding, transferase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 40851.06 |
Authors | Holden, H.M.,Thoden, J.B. (deposition date: 2010-07-15, release date: 2010-07-28, Last modification date: 2023-09-06) |
Primary citation | Dow, G.T.,Gilbert, M.,Thoden, J.B.,Holden, H.M. Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase. Protein Sci., 26:586-599, 2017 Cited by PubMed: 28028852DOI: 10.1002/pro.3109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.301 Å) |
Structure validation
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