3NYJ
Crystal Structure Analysis of APP E2 domain
Summary for 3NYJ
Entry DOI | 10.2210/pdb3nyj/pdb |
Descriptor | Amyloid beta A4 protein, OSMIUM ION (3 entities in total) |
Functional Keywords | alzheimer's disease, helical hairpin, protein fibril |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 1 |
Total formula weight | 24960.97 |
Authors | |
Primary citation | Lee, S.,Xue, Y.,Hu, J.,Wang, Y.,Liu, X.,Demeler, B.,Ha, Y. The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50:5453-5464, 2011 Cited by PubMed: 21574595DOI: 10.1021/bi101846x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report