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3NY9

Crystal structure of the human beta2 adrenergic receptor in complex with a novel inverse agonist

Summary for 3NY9
Entry DOI10.2210/pdb3ny9/pdb
Related2RH1 3D4S 3NY8 3NYA
DescriptorBeta-2 adrenergic receptor, Lysozyme, CHOLESTEROL, ethyl 4-({(2S)-2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)-3-methyl-1-benzofuran-2-carboxylate, ... (5 entities in total)
Functional Keywordsg protein-coupled receptor, lysozyme, fusion, transducer, adrenergic, g-proteins, arrestins, adrenalin, compound 2, glycosylation, palmitoylation, phosphorylation, membrane protein, hydrolase, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, gpcr network, gpcr
Biological sourceHomo sapiens
More
Cellular locationCell membrane ; Multi- pass membrane protein : P07550
Total number of polymer chains1
Total formula weight57423.17
Authors
Primary citationWacker, D.,Fenalti, G.,Brown, M.A.,Katritch, V.,Abagyan, R.,Cherezov, V.,Stevens, R.C.
Conserved Binding Mode of Human beta(2) Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
J.Am.Chem.Soc., 132:11443-11445, 2010
Cited by
PubMed: 20669948
DOI: 10.1021/ja105108q
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.84 Å)
Structure validation

217705

數據於2024-03-27公開中

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