3NY6

Catalytic fragment of cholix toxin from vibrio cholerae in complex with inhibitor V30

3NY6 の概要

• エントリーDOI: 10.2210/pdb3ny6/pdb
• 関連するPDBエントリー: 2Q6M 3ESS 3KI0 3KI1 3KI2 3KI3 3KI4 3KI5 3KI6 3KI7
• 分子名称: Cholix toxin, GLYCEROL, 2-[(5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(2-hydroxyethyl)acetamide, ... (5 entities in total)
• 機能のキーワード: alpha-beta complex, adp-ribosyl transferase, nad+ binding, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Vibrio cholerae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23927.40

構造登録者

Merrill, A.R.,Jorgensen, R. (登録日: 2010-07-14, 公開日: 2010-12-29, 最終更新日: 2023-09-06)

• 主引用文献: Turgeon, Z.,Jorgensen, R.,Visschedyk, D.,Edwards, P.R.,Legree, S.,McGregor, C.,Fieldhouse, R.J.,Mangroo, D.,Schapira, M.,Merrill, A.R.; Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins.; Antimicrob.Agents Chemother., 55:983-991, 2011; PubMed: 21135177; DOI: 10.1128/AAC.01164-10

実験手法

X-RAY DIFFRACTION (1.68 Å)