3NV8

The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol pyruvate and manganese (thesit-free)

3NV8 の概要

• エントリーDOI: 10.2210/pdb3nv8/pdb
• 関連するPDBエントリー: 2B7O 3KGF 3NUD 3NUE
• 分子名称: Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, SULFATE ION, MANGANESE (II) ION, ... (8 entities in total)
• 機能のキーワード: dah7p synthase, shikimate pathway, aromatic amino-acid biosynthesis, evolutionary relationships, augmented tim-barrel structure, tim barrel, aldolase, cytosol, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102905.88

構造登録者

Parker, E.J.,Jameson, G.B.,Jiao, W.,Hutton, R.H.,Webby, C.J.,Baker, E.N.,Baker, H.M. (登録日: 2010-07-08, 公開日: 2010-07-28, 最終更新日: 2023-11-01)

• 主引用文献: Webby, C.J.,Jiao, W.,Hutton, R.D.,Blackmore, N.J.,Baker, H.M.,Baker, E.N.,Jameson, G.B.,Parker, E.J.; Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis; J.Biol.Chem., 285:30567-30576, 2010; PubMed: 20667835; DOI: 10.1074/jbc.M110.111856

実験手法

X-RAY DIFFRACTION (2.25 Å)