3NPZ

Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)

3NPZ の概要

• エントリーDOI: 10.2210/pdb3npz/pdb
• 分子名称: Prolactin, Prolactin receptor (2 entities in total)
• 機能のキーワード: protein protein complex, hormone-receptor complex, hormone, hormone-hormone receptor complex, hormone/hormone receptor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01236; Membrane; Single-pass type I membrane protein: P05710
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 74733.04

構造登録者

Van Agthoven, J.,England, P.,Goffin, V.,Broutin, I. (登録日: 2010-06-29, 公開日: 2010-10-06, 最終更新日: 2023-09-06)

• 主引用文献: van Agthoven, J.,Zhang, C.,Tallet, E.,Raynal, B.,Hoos, S.,Baron, B.,England, P.,Goffin, V.,Broutin, I.; Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.; J.Mol.Biol., 404:112-126, 2010; PubMed: 20875426; DOI: 10.1016/j.jmb.2010.09.036

実験手法

X-RAY DIFFRACTION (3.35 Å)