3NP5

Crystal structure of an abridged form of the mature ectodomain of the human receptor-type protein tyrosine phosphatase ICA512/IA-2 AT pH 4.5

Summary for 3NP5

• Entry DOI: 10.2210/pdb3np5/pdb
• Related: 2QT7 3N0I 3N4W 3NG8
• Descriptor: Receptor-type tyrosine-protein phosphatase-like N, CALCIUM ION (3 entities in total)
• Functional Keywords: ia-2, ica-512, protein-tyrosine phosphatase, transmembrane protein, diabetes, autoimmunity, proteolysis, glycoprotein, receptor, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: Q16849
• Total number of polymer chains: 4
• Total formula weight: 38631.82

Authors

Primo, M.E.,Jakoncic, J.,Poskus, E.,Ermacora, M.R. (deposition date: 2010-06-27, release date: 2010-12-29, Last modification date: 2023-09-06)

• Primary citation: Primo, M.E.,Jakoncic, J.,Poskus, E.,Ermacora, M.R.; Receptor-Type Protein-Tyrosine Phosphatase Ia-2-Ica512; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)