3NMA

Mutant P169S of Foot-and-mouth disease Virus RNA dependent RNA-polymerase

Summary for 3NMA

• Entry DOI: 10.2210/pdb3nma/pdb
• Related: 1u09 1wne 2E9R 2E9T 2E9Z 2EC0 3NKY 3NL0
• Descriptor: Genome polyprotein, 5'-R(*GP*GP*C)-3', 5'-R(P*CP*C)-3', ... (5 entities in total)
• Functional Keywords: foot-and-mouth disease virus, 3d polymerase rna-dependent rna polymerase, picornavirus, ribavirin, transferase-rna complex, transferase/rna
• Biological source: Foot and mouth disease virus C; More
• Total number of polymer chains: 3
• Total formula weight: 54958.96

Authors

Agudo, R.,Ferrer-Orta, C.,Arias, A.,Perez-Luque, R.,Verdaguer, N.,Domingo, E. (deposition date: 2010-06-22, release date: 2011-05-25, Last modification date: 2023-11-01)

• Primary citation: Agudo, R.,Ferrer-Orta, C.,Arias, A.,de la Higuera, I.,Perales, C.,Perez-Luque, R.,Verdaguer, N.,Domingo, E.; A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.; Plos Pathog., 6:e1001072-e1001072, 2010; PubMed: 20865120; DOI: 10.1371/journal.ppat.1001072

Experimental method

X-RAY DIFFRACTION (2.6 Å)