3NM1

The Crystal Structure of Candida glabrata THI6, a Bifunctional Enzyme involved in Thiamin Biosyhthesis of Eukaryotes

Summary for 3NM1

Entry DOI	10.2210/pdb3nm1/pdb
Related	3NL2 3NL3 3NL5 3NL6 3NM3
Descriptor	Thiamine biosynthetic bifunctional enzyme, 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, ... (5 entities in total)
Functional Keywords	thi6, bifunctional enzyme, thiamin biosynthesis, eukaryoyes, transferase
Biological source	Candida glabrata (Yeast)
Total number of polymer chains	6
Total formula weight	352518.92
Authors	Paul, D.,Chatterjee, A.,Begley, T.P.,Ealick, S.E. (deposition date: 2010-06-21, release date: 2010-11-10, Last modification date: 2024-02-21)
Primary citation	Paul, D.,Chatterjee, A.,Begley, T.P.,Ealick, S.E. Domain Organization in Candida glabrata THI6, a Bifunctional Enzyme Required for Thiamin Biosynthesis in Eukaryotes . Biochemistry, 49:9922-9934, 2010 Cited by PubMed: 20968298 DOI: 10.1021/bi101008u PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.211 Å)

Structure validation