3NJQ
Crystal structure of Kaposi's sarcoma-associated herpesvirus protease in complex with dimer disruptor
Summary for 3NJQ
Entry DOI | 10.2210/pdb3njq/pdb |
Descriptor | ORF 17, ACETATE ION, 3-benzyl-4-({[6-(cyclohexylmethyl)pyridin-2-yl]carbonyl}amino)benzoic acid, ... (7 entities in total) |
Functional Keywords | protein-dimer disruptor complex, kshv, kshv protease, herpesvirus protease, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Human herpesvirus 8 type M More |
Total number of polymer chains | 2 |
Total formula weight | 44159.12 |
Authors | Baharuddin, A. (deposition date: 2010-06-17, release date: 2011-08-17, Last modification date: 2017-11-08) |
Primary citation | Lee, G.M.,Shahian, T.,Baharuddin, A.,Gable, J.E.,Craik, C.S. Enzyme inhibition by allosteric capture of an inactive conformation. J.Mol.Biol., 411:999-1016, 2011 Cited by PubMed: 21723875DOI: 10.1016/j.jmb.2011.06.032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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