3NHD
GYVLGS segment 127-132 from human prion with V129
Summary for 3NHD
Entry DOI | 10.2210/pdb3nhd/pdb |
Related | 3NHC |
Descriptor | Major prion protein, ACETIC ACID (3 entities in total) |
Functional Keywords | amyloid-like protofibril, protein fibril |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156 |
Total number of polymer chains | 2 |
Total formula weight | 1309.42 |
Authors | Apostol, M.I.,Eisenberg, D. (deposition date: 2010-06-14, release date: 2010-08-04, Last modification date: 2024-05-22) |
Primary citation | Apostol, M.I.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J.Biol.Chem., 285:29671-29675, 2010 Cited by PubMed: 20685658DOI: 10.1074/jbc.C110.158303 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
Download full validation report