3NG7
Complex of dithionite-reduced 6-hydroxy-L-nicotine oxidase with substrate bound at active site and inhibitor at exit cavity
Summary for 3NG7
| Entry DOI | 10.2210/pdb3ng7/pdb |
| Related | 3K7M 3K7Q 3K7T |
| Descriptor | 6-hydroxy-L-nicotine oxidase, 5-[(2S)-1-methylpyrrolidin-2-yl]pyridin-2-ol, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total) |
| Functional Keywords | enantiomeric substrate-inhibitor, flavoenzymes, nicotine degradation, oxidase, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Arthrobacter nicotinovorans |
| Total number of polymer chains | 1 |
| Total formula weight | 49030.00 |
| Authors | Kachalova, G.S.,Bartunik, H.D. (deposition date: 2010-06-11, release date: 2011-03-16, Last modification date: 2023-11-01) |
| Primary citation | Kachalova, G.,Decker, K.,Holt, A.,Bartunik, H.D. Crystallographic snapshots of the complete reaction cycle of nicotine degradation by an amine oxidase of the monoamine oxidase (MAO) family Proc.Natl.Acad.Sci.USA, 108:4800-4805, 2011 Cited by PubMed: 21383134DOI: 10.1073/pnas.1016684108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report
