3NEE
Wild type human transthyretin (TTR) complexed with GC-1 (TTRwt:GC-1)
Summary for 3NEE
Entry DOI | 10.2210/pdb3nee/pdb |
Related | 3CFM 3KGS 3KGT 3KGU 3NEO 3NES 3NEX |
Descriptor | Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transport protein, ttr, transthyretin, amyloid, ligand, gc-1 |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 26155.33 |
Authors | Trivella, D.B.B.,Polikarpov, I. (deposition date: 2010-06-08, release date: 2010-11-24, Last modification date: 2024-02-21) |
Primary citation | Trivella, D.B.,Sairre, M.I.,Foguel, D.,Lima, L.M.,Polikarpov, I. The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition. J.Struct.Biol., 173:323-332, 2011 Cited by PubMed: 20937391DOI: 10.1016/j.jsb.2010.10.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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