3N9R
Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with N-(4-hydroxybutyl)-phosphoglycolohydroxamic acid, a competitive inhibitor
Summary for 3N9R
Entry DOI | 10.2210/pdb3n9r/pdb |
Related | 3C4U 3C52 3C56 3N9S |
Descriptor | Fructose-bisphosphate aldolase, ZINC ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | fbp aldolase, class ii, inhibitor, lyase |
Biological source | Helicobacter pylori |
Total number of polymer chains | 8 |
Total formula weight | 273342.53 |
Authors | Coincon, M.,Sygusch, S. (deposition date: 2010-05-31, release date: 2010-11-17, Last modification date: 2023-09-06) |
Primary citation | Daher, R.,Fonvielle, M.,Gest, P.M.,Guerin, M.E.,Jackson, M.,Sygusch, J.,Therisod, M. Rational Design, Synthesis, and Evaluation of New Selective Inhibitors of Microbial Class II (Zinc Dependent) Fructose Bis-phosphate Aldolases. J.Med.Chem., 53:7836-7842, 2010 Cited by PubMed: 20929256DOI: 10.1021/jm1009814 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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