3N8Z
Crystal Structure of Cyclooxygenase-1 in Complex with Flurbiprofen
Summary for 3N8Z
| Entry DOI | 10.2210/pdb3n8z/pdb |
| Related | 3N8V 3N8W 3N8X 3N8Y |
| Descriptor | Prostaglandin G/H synthase 1, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
| Functional Keywords | cox-1, cyclooxygenase, peroxidase, prostaglandin, heme, flurbiprofen, merohedral twinned, oxidoreductase |
| Biological source | Ovis aries (sheep) |
| Total number of polymer chains | 2 |
| Total formula weight | 133240.05 |
| Authors | Sidhu, R.S. (deposition date: 2010-05-28, release date: 2010-07-28, Last modification date: 2023-09-06) |
| Primary citation | Sidhu, R.S.,Lee, J.Y.,Yuan, C.,Smith, W.L. Comparison of Cyclooxygenase-1 Crystal Structures: Cross-Talk between Monomers Comprising Cyclooxygenase-1 Homodimers Biochemistry, 49:7069-7079, 2010 Cited by PubMed: 20669977DOI: 10.1021/bi1003298 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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