3N6S

Crystal structure of human mitochondrial mTERF in complex with a 15-mer DNA encompassing the tRNALeu(UUR) binding sequence

Summary for 3N6S

• Entry DOI: 10.2210/pdb3n6s/pdb
• Related: 3N7Q
• Descriptor: Transcription termination factor, mitochondrial, DNA (5'-D(*AP*TP*GP*GP*CP*AP*GP*AP*GP*CP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*CP*A)-3') (3 entities in total)
• Functional Keywords: mitochondrial transcription termination factor-dna complex, mitochondrial replication pausing-dna complex, left-handed helical tandem repeat, protein-dna complex, transcription, replication-dna complex, replication/dna
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion: Q99551
• Total number of polymer chains: 3
• Total formula weight: 49830.01

Authors

Jimenez-Menendez, N.,Fernandez-Millan, P.,Rubio-Cosials, A.,Arnan, C.,Montoya, J.,Jacobs, H.T.,Bernado, P.,Coll, M.,Uson, I.,Sola, M. (deposition date: 2010-05-26, release date: 2010-06-16, Last modification date: 2024-02-21)

• Primary citation: Jimenez-Menendez, N.,Fernandez-Millan, P.,Rubio-Cosials, A.,Arnan, C.,Montoya, J.,Jacobs, H.T.,Bernado, P.,Coll, M.,Uson, I.,Sola, M.; Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat.; Nat.Struct.Mol.Biol., 17:891-893, 2010; PubMed: 20543826; DOI: 10.1038/nsmb.1859

Experimental method

X-RAY DIFFRACTION (3.1 Å)