3N5N
Crystal structure analysis of the catalytic domain and interdomain connector of human MutY homologue
Summary for 3N5N
Entry DOI | 10.2210/pdb3n5n/pdb |
Descriptor | A/G-specific adenine DNA glycosylase, IRON/SULFUR CLUSTER, ACETATE ION, ... (4 entities in total) |
Functional Keywords | alpha-helices, helix-hairpin-helix motif, iron-sulfur cluster, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UIF7 |
Total number of polymer chains | 2 |
Total formula weight | 64271.96 |
Authors | Toth, E.A.,Luncsford, P.J. (deposition date: 2010-05-25, release date: 2010-11-10, Last modification date: 2023-09-06) |
Primary citation | Luncsford, P.J.,Chang, D.Y.,Shi, G.,Bernstein, J.,Madabushi, A.,Patterson, D.N.,Lu, A.L.,Toth, E.A. A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. J.Mol.Biol., 403:351-370, 2010 Cited by PubMed: 20816984DOI: 10.1016/j.jmb.2010.08.045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report