3N4O

Insights into the stabilizing contributions of a bicyclic cytosine analogue: crystal structures of DNA duplexes containing 7,8-dihydropyrido[2,3-d]pyrimidin-2-one

Summary for 3N4O

• Entry DOI: 10.2210/pdb3n4o/pdb
• Related: 3GJJ 3N4N
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(B7C)P*CP*GP*CP*G)-3', 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE (3 entities in total)
• Functional Keywords: bicyclic cytosine, dna
• Total number of polymer chains: 2
• Total formula weight: 7797.36

Authors

Takenaka, A.,Juan, E.C.M.,Shimizu, S. (deposition date: 2010-05-22, release date: 2010-08-11, Last modification date: 2023-11-01)

• Primary citation: Juan, E.C.M.,Shimizu, S.,Ma, X.,Kurose, T.,Haraguchi, T.,Zhang, F.,Tsunoda, M.,Ohkubo, A.,Sekine, M.,Shibata, T.,Millington, C.L.,Williams, D.M.,Takenaka, A.; Insights into the DNA stabilizing contributions of a bicyclic cytosine analogue: crystal structures of DNA duplexes containing 7,8-dihydropyrido [2,3-d]pyrimidin-2-one.; Nucleic Acids Res., 2010; PubMed: 20554855; DOI: 10.1093/nar/gkq519

Experimental method

X-RAY DIFFRACTION (2.9 Å)