3N3Z

Crystal structure of PDE9A (E406A) mutant in complex with IBMX

Summary for 3N3Z

• Entry DOI: 10.2210/pdb3n3z/pdb
• Descriptor: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, 3-ISOBUTYL-1-METHYLXANTHINE, ZINC ION, ... (6 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Isoform PDE9A1: Cell projection, ruffle membrane. Isoform PDE9A2: Cell projection, ruffle membrane. Isoform PDE9A3: Cytoplasm. Isoform PDE9A17: Cytoplasm: O76083
• Total number of polymer chains: 2
• Total formula weight: 77636.44

Authors

Hou, J.,Luo, H.-B.,Chen, Y.,Xu, J.,Zhao, R.,Zou, L. (deposition date: 2010-05-21, release date: 2011-04-13, Last modification date: 2023-11-01)

• Primary citation: Hou, J.,Luo, H.-B.,Chen, Y.,Xu, J.,Zhao, R.,Zou, L.; Crystal structure of PDE9A (E406A) mutation in complex with IBMX; To be Published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)