3N23
Crystal structure of the high affinity complex between ouabain and the E2P form of the sodium-potassium pump
Summary for 3N23
Entry DOI | 10.2210/pdb3n23/pdb |
Related | 3B9B 3KDP 3N2F |
Descriptor | Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ... (5 entities in total) |
Functional Keywords | sodium-potassium pump, p-type atpase, ouabain, cardiotonic steroids, hydrolase |
Biological source | Sus scrofa (pigs) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P05024 Cell membrane; Single-pass type II membrane protein: P05027 |
Total number of polymer chains | 6 |
Total formula weight | 291749.44 |
Authors | Yatime, L.,Laursen, M.,Morth, J.P.,Esmann, M.,Nissen, P.,Fedosova, N.U. (deposition date: 2010-05-17, release date: 2011-01-19, Last modification date: 2014-09-17) |
Primary citation | Yatime, L.,Laursen, M.,Morth, J.P.,Esmann, M.,Nissen, P.,Fedosova, N.U. Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase. J.Struct.Biol., 174:296-306, 2011 Cited by PubMed: 21182963DOI: 10.1016/j.jsb.2010.12.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.6 Å) |
Structure validation
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