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3N0T

Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A

Summary for 3N0T
Entry DOI10.2210/pdb3n0t/pdb
Related3JYH
DescriptorDipeptidyl peptidase 2, (3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine (3 entities in total)
Functional Keywordsstructural genomics, structural genomics consortium, sgc, aminopeptidase, cleavage on pair of basic residues, cytoplasmic vesicle, glycoprotein, hydrolase, lysosome, protease, serine protease, zymogen
Biological sourceHomo sapiens (human)
Cellular locationLysosome : Q9UHL4
Total number of polymer chains4
Total formula weight208914.44
Authors
Primary citationDobrovetsky, E.,Khutoreskaya, G.,Seitova, A.,Crombet, L.,Cossar, D.,Pagannon, S.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Hassell, A.,Shewchuk, L.,Haffner, C.,Bochkarev, A.
Human dipeptidyl peptidase DPP7
To be Published,
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

217705

數據於2024-03-27公開中

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