3N0T
Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A
Summary for 3N0T
Entry DOI | 10.2210/pdb3n0t/pdb |
Related | 3JYH |
Descriptor | Dipeptidyl peptidase 2, (3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine (3 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, aminopeptidase, cleavage on pair of basic residues, cytoplasmic vesicle, glycoprotein, hydrolase, lysosome, protease, serine protease, zymogen |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome : Q9UHL4 |
Total number of polymer chains | 4 |
Total formula weight | 208914.44 |
Authors | Dobrovetsky, E.,Khutoreskaya, G.,Seitova, A.,Crombet, L.,Cossar, D.,Pagannon, S.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Hassell, A.,Shewchuk, L.,Haffner, C.,Bochkarev, A.,Structural Genomics Consortium (SGC) (deposition date: 2010-05-14, release date: 2010-07-21, Last modification date: 2023-09-06) |
Primary citation | Dobrovetsky, E.,Khutoreskaya, G.,Seitova, A.,Crombet, L.,Cossar, D.,Pagannon, S.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Hassell, A.,Shewchuk, L.,Haffner, C.,Bochkarev, A. Human dipeptidyl peptidase DPP7 To be Published, |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
Download full validation report