3N0T

Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A

3N0T の概要

• エントリーDOI: 10.2210/pdb3n0t/pdb
• 関連するPDBエントリー: 3JYH
• 分子名称: Dipeptidyl peptidase 2, (3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine (3 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, aminopeptidase, cleavage on pair of basic residues, cytoplasmic vesicle, glycoprotein, hydrolase, lysosome, protease, serine protease, zymogen
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Lysosome : Q9UHL4
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 208914.44

構造登録者

Dobrovetsky, E.,Khutoreskaya, G.,Seitova, A.,Crombet, L.,Cossar, D.,Pagannon, S.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Hassell, A.,Shewchuk, L.,Haffner, C.,Bochkarev, A.,Structural Genomics Consortium (SGC) (登録日: 2010-05-14, 公開日: 2010-07-21, 最終更新日: 2023-09-06)

• 主引用文献: Dobrovetsky, E.,Khutoreskaya, G.,Seitova, A.,Crombet, L.,Cossar, D.,Pagannon, S.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Hassell, A.,Shewchuk, L.,Haffner, C.,Bochkarev, A.; Human dipeptidyl peptidase DPP7; To be Published,

実験手法

X-RAY DIFFRACTION (2.45 Å)