3MY5

CDk2/cyclinA in complex with DRB

Summary for 3MY5

• Entry DOI: 10.2210/pdb3my5/pdb
• Related: 3MY1
• Descriptor: Cell division protein kinase 2, Cyclin-A2, 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, ... (6 entities in total)
• Functional Keywords: cdk, cyclin, inhibitor, drb, transferase-protein binding-inhibitor complex, transferase/protein binding/inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P30274
• Total number of polymer chains: 4
• Total formula weight: 129431.14

Authors

Baumli, S.,Johnson, L.N. (deposition date: 2010-05-09, release date: 2010-09-29, Last modification date: 2023-11-01)

• Primary citation: Baumli, S.,Endicott, J.A.,Johnson, L.N.; Halogen bonds form the basis for selective P-TEFb inhibition by DRB; Chem.Biol., 17:931-936, 2010; PubMed: 20851342; DOI: 10.1016/j.chembiol.2010.07.012

Experimental method

X-RAY DIFFRACTION (2.1 Å)