3MXV
Crystal structure of fab fragment of anti-Shh 5E1 chimera
Summary for 3MXV
Entry DOI | 10.2210/pdb3mxv/pdb |
Related | 3MXW |
Descriptor | fab fragment of anti-Shh 5E1 mouse/human chimera, light chain, fab fragment of anti-Shh 5E1 mouse/human chimera, heavy chain, SULFATE ION, ... (4 entities in total) |
Functional Keywords | chimera, fab fragment, antibody, sonic hedgehog, immune system |
Biological source | Mus musculus, Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 48013.31 |
Authors | Hymowitz, S.G.,Maun, H.R. (deposition date: 2010-05-07, release date: 2010-05-26, Last modification date: 2023-09-06) |
Primary citation | Maun, H.R.,Wen, X.,Lingel, A.,de Sauvage, F.J.,Lazarus, R.A.,Scales, S.J.,Hymowitz, S.G. Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site. J.Biol.Chem., 285:26570-26580, 2010 Cited by PubMed: 20504762DOI: 10.1074/jbc.M110.112284 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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