3MX6

Crystal structure of methionine aminopeptidase from Rickettsia prowazekii bound to methionine

Summary for 3MX6

• Entry DOI: 10.2210/pdb3mx6/pdb
• Related: 3MR1
• Descriptor: Methionine aminopeptidase, METHIONINE, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: seattle structural genomics center for infectious disease, ssgcid, aminopeptidase, protease, epidermic typhus, lice-born pathogen, hydrolase
• Biological source: Rickettsia prowazekii
• Total number of polymer chains: 2
• Total formula weight: 58758.72

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2010-05-06, release date: 2010-05-26, Last modification date: 2023-09-06)

• Primary citation: Helgren, T.R.,Chen, C.,Wangtrakuldee, P.,Edwards, T.E.,Staker, B.L.,Abendroth, J.,Sankaran, B.,Housley, N.A.,Myler, P.J.,Audia, J.P.,Horn, J.R.,Hagen, T.J.; Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents.; Bioorg.Med.Chem., 25:813-824, 2017; PubMed: 28089350; DOI: 10.1016/j.bmc.2016.11.013

Experimental method

X-RAY DIFFRACTION (1.7 Å)