3MVR

Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation

Summary for 3MVR

Entry DOI	10.2210/pdb3mvr/pdb
Related	1PO5 1SUO 2BDM 2Q6N 3G5N
Descriptor	Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... (4 entities in total)
Functional Keywords	ligand free closed conformation, p450, cytochrome p450 2b4, monooxygenase, oxidoreductase, membrane protein, cyp 2b4.
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Endoplasmic reticulum membrane; Peripheral membrane protein: P00178
Total number of polymer chains	2
Total formula weight	111549.43
Authors	Shah, M.B.,Stout, C.D.,Halpert, J.R. (deposition date: 2010-05-04, release date: 2010-09-29, Last modification date: 2023-09-06)
Primary citation	Wilderman, P.R.,Shah, M.B.,Liu, T.,Li, S.,Hsu, S.,Roberts, A.G.,Goodlett, D.R.,Zhang, Q.,Woods, V.L.,Stout, C.D.,Halpert, J.R. Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography. J.Biol.Chem., 285:38602-38611, 2010 Cited by PubMed: 20880847 DOI: 10.1074/jbc.M110.180646 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation