3MVR
Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytochrome P450 2B4 | polymer | 476 | 54169.1 | 2 | UniProt (P00178) Pfam (PF00067) | Oryctolagus cuniculus (rabbit) | CYPIIB4, Cytochrome P450 isozyme 2, Cytochrome P450 LM2, Cytochrome P450 type B0, Cytochrome P450 type B1 |
| 2 | C, F (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, E, G, H (A, B) | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE | non-polymer | 494.6 | 4 | Chemie (CM5) PubChem (44483217) PubChem (46897875) PubChem (59518660) PubChem (68343857) PubChem (58112563) PubChem (73659147) PubChem (5142094) PubChem (70796429) PubChem (70839941) PubChem (70863059) PubChem (89951995) PubChem (92132104) PubChem (5327073) PubChem (126731025) PubChem (126735874) PubChem (133612054) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 729 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 491 (UniProt: P00178)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | expression tag |
| Ala 21 | - | expression tag |
| Lys 22 | Gly 22 | engineered mutation |
| Lys 23 | His 23 | engineered mutation |
| Thr 24 | Pro 24 | engineered mutation |
| Ser 25 | Lys 25 | engineered mutation |
| Ser 26 | Ala 26 | engineered mutation |
| Lys 27 | His 27 | engineered mutation |
| Lys 29 | Arg 29 | engineered mutation |
| Ser 221 | Pro 221 | engineered mutation |
| Tyr 226 | His 226 | engineered mutation |
| His 492 | - | expression tag |
| His 493 | - | expression tag |
| His 494 | - | expression tag |
| His 495 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 108338.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3211.3 | |
| All* | Total formula weight | 111549.4 |
