3MUU

Crystal structure of the Sindbis virus E2-E1 heterodimer at low pH

3MUU の概要

• エントリーDOI: 10.2210/pdb3muu/pdb
• 分子名称: Structural polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: beta barrels, ig-like folds, viral protein
• 由来する生物種: Sindbis virus (SINV); 詳細
• 細胞内の位置: Capsid protein: Virion . p62: Virion membrane ; Single- pass type I membrane protein . E2 envelope glycoprotein: Virion membrane ; Single-pass type I membrane protein . E1 envelope glycoprotein: Virion membrane ; Single-pass type I membrane protein . 6K protein: Host cell membrane ; Multi-pass membrane protein : P03316
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 505014.78

構造登録者

Li, L.,Jose, J.,Xiang, Y.,Kuhn, R.J.,Rossmann, M.G. (登録日: 2010-05-03, 公開日: 2010-11-24, 最終更新日: 2020-07-29)

• 主引用文献: Li, L.,Jose, J.,Xiang, Y.,Kuhn, R.J.,Rossmann, M.G.; Structural changes of envelope proteins during alphavirus fusion.; Nature, 468:705-708, 2010; PubMed: 21124457; DOI: 10.1038/nature09546

実験手法

X-RAY DIFFRACTION (3.29 Å)