3MUK

Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23

Summary for 3MUK

• Entry DOI: 10.2210/pdb3muk/pdb
• Related: 3JVJ 3JVK 3MUL
• Descriptor: Bromodomain-containing protein 4, peptide of Histone H3.3, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bromodomain, histone recognition, n-propionyl lysine, acylation, signaling protein
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus: Q9ESU6 P84243
• Total number of polymer chains: 2
• Total formula weight: 16337.77

Authors

Vollmuth, F.,Geyer, M. (deposition date: 2010-05-03, release date: 2010-08-11, Last modification date: 2023-11-01)

• Primary citation: Vollmuth, F.,Geyer, M.; Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains; Angew.Chem.Int.Ed.Engl., 49:6768-6772, 2010; PubMed: 20715035; DOI: 10.1002/anie.201002724

Experimental method

X-RAY DIFFRACTION (1.75 Å)