3MUK
Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1 |
| Chain | Residue |
| A | ILE100 |
| A | ILE101 |
| A | LYS102 |
| A | THR103 |
| A | ASN135 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA80-TYR139 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| D | PRK3 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Citrulline => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| D | ARG6 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:17194708, ECO:0000269|PubMed:7309716 |
| Chain | Residue | Details |
| D | LYS7 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15684425, ECO:0000269|PubMed:15851689, ECO:0000269|PubMed:16185088 |
| Chain | Residue | Details |
| D | SER8 |
