3MP4
Crystal structure of Human lyase R41M mutant
Summary for 3MP4
Entry DOI | 10.2210/pdb3mp4/pdb |
Related | 2cw6 3MP3 3MP5 |
Descriptor | Hydroxymethylglutaryl-CoA lyase (2 entities in total) |
Functional Keywords | ketogenic enzyme, human hmg-coa lyase, r41m, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P35914 |
Total number of polymer chains | 6 |
Total formula weight | 189309.79 |
Authors | Fu, Z.,Runquist, J.A.,Montgomery, C.,Miziorko, H.M.,Kim, J.-J.P. (deposition date: 2010-04-24, release date: 2010-06-16, Last modification date: 2023-09-06) |
Primary citation | Fu, Z.,Runquist, J.A.,Montgomery, C.,Miziorko, H.M.,Kim, J.J. Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes. J.Biol.Chem., 285:26341-26349, 2010 Cited by PubMed: 20558737DOI: 10.1074/jbc.M110.139931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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