3MOR

Crystal structure of Cathepsin B from Trypanosoma Brucei

Summary for 3MOR

Related1HUC 1QDQ
DescriptorCathepsin B-like cysteine protease, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ... (6 entities in total)
Functional Keywordsthiol protease, hydrolase
Biological sourceTrypanosoma brucei
Total number of polymer chains2
Total molecular weight71282.41
Authors
Cupelli, K.,Stehle, T. (deposition date: 2010-04-23, release date: 2011-11-02, Last modification date: 2012-06-20)
Primary citation
Koopmann, R.,Cupelli, K.,Redecke, L.,Nass, K.,Deponte, D.P.,White, T.A.,Stellato, F.,Rehders, D.,Liang, M.,Andreasson, J.,Aquila, A.,Bajt, S.,Barthelmess, M.,Barty, A.,Bogan, M.J.,Bostedt, C.,Boutet, S.,Bozek, J.D.,Caleman, C.,Coppola, N.,Davidsson, J.,Doak, R.B.,Ekeberg, T.,Epp, S.W.,Erk, B.,Fleckenstein, H.,Foucar, L.,Graafsma, H.,Gumprecht, L.,Hajdu, J.,Hampton, C.Y.,Hartmann, A.,Hartmann, R.,Hauser, G.,Hirsemann, H.,Holl, P.,Hunter, M.S.,Kassemeyer, S.,Kirian, R.A.,Lomb, L.,Maia, F.R.,Kimmel, N.,Martin, A.V.,Messerschmidt, M.,Reich, C.,Rolles, D.,Rudek, B.,Rudenko, A.,Schlichting, I.,Schulz, J.,Seibert, M.M.,Shoeman, R.L.,Sierra, R.G.,Soltau, H.,Stern, S.,Struder, L.,Timneanu, N.,Ullrich, J.,Wang, X.,Weidenspointner, G.,Weierstall, U.,Williams, G.J.,Wunderer, C.B.,Fromme, P.,Spence, J.C.,Stehle, T.,Chapman, H.N.,Betzel, C.,Duszenko, M.
In vivo protein crystallization opens new routes in structural biology.
Nat.Methods, 9:259-262, 2012
PubMed: 22286384 (PDB entries with the same primary citation)
DOI: 10.1038/nmeth.1859
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.55 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24530.6%2.1%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report