3MNU

Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron containing aromatic sulfamide with mammalian isoforms I-XV

Summary for 3MNU

Entry DOI	10.2210/pdb3mnu/pdb
Related	1CA2
Descriptor	Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (7 entities in total)
Functional Keywords	protein-inhibitor complex, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00918
Total number of polymer chains	1
Total formula weight	30031.30
Authors	Di Fiore, A.,De Simone, G. (deposition date: 2010-04-22, release date: 2010-06-16, Last modification date: 2023-09-06)
Primary citation	Di Fiore, A.,Monti, S.M.,Innocenti, A.,Winum, J.Y.,De Simone, G.,Supuran, C.T. Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. Bioorg.Med.Chem.Lett., 20:3601-3605, 2010 Cited by PubMed: 20472429 DOI: 10.1016/j.bmcl.2010.04.114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation