3MNL
The crystal structure of KstR (Rv3574) from Mycobacterium tuberculosis H37Rv
Summary for 3MNL
Entry DOI | 10.2210/pdb3mnl/pdb |
Related | 5CW8 5CXG 5CXI |
Descriptor | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY), TRIETHYLENE GLYCOL (3 entities in total) |
Functional Keywords | tetr family of transcriptional regulator, all-helical, dna-binding, hydrophobic ligand-binding, structural genomics, tb structural genomics consortium, tbsgc, transcription regulator |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 44923.18 |
Authors | Gao, C.,Bunker, R.D.,ten Bokum, A.,Kendall, S.L.,Stoker, N.G.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2010-04-21, release date: 2011-04-27, Last modification date: 2023-11-01) |
Primary citation | Ho, N.A.,Dawes, S.S.,Crowe, A.M.,Casabon, I.,Gao, C.,Kendall, S.L.,Baker, E.N.,Eltis, L.D.,Lott, J.S. The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. J. Biol. Chem., 291:7256-7266, 2016 Cited by PubMed: 26858250DOI: 10.1074/jbc.M115.707760 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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