3MNL

The crystal structure of KstR (Rv3574) from Mycobacterium tuberculosis H37Rv

Summary for 3MNL

Entry DOI	10.2210/pdb3mnl/pdb
Related	5CW8 5CXG 5CXI
Descriptor	TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY), TRIETHYLENE GLYCOL (3 entities in total)
Functional Keywords	tetr family of transcriptional regulator, all-helical, dna-binding, hydrophobic ligand-binding, structural genomics, tb structural genomics consortium, tbsgc, transcription regulator
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	44923.18
Authors	Gao, C.,Bunker, R.D.,ten Bokum, A.,Kendall, S.L.,Stoker, N.G.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2010-04-21, release date: 2011-04-27, Last modification date: 2023-11-01)
Primary citation	Ho, N.A.,Dawes, S.S.,Crowe, A.M.,Casabon, I.,Gao, C.,Kendall, S.L.,Baker, E.N.,Eltis, L.D.,Lott, J.S. The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. J. Biol. Chem., 291:7256-7266, 2016 Cited by PubMed: 26858250 DOI: 10.1074/jbc.M115.707760 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation