3MNL

The crystal structure of KstR (Rv3574) from Mycobacterium tuberculosis H37Rv

3MNL の概要

• エントリーDOI: 10.2210/pdb3mnl/pdb
• 関連するPDBエントリー: 5CW8 5CXG 5CXI
• 分子名称: TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY), TRIETHYLENE GLYCOL (3 entities in total)
• 機能のキーワード: tetr family of transcriptional regulator, all-helical, dna-binding, hydrophobic ligand-binding, structural genomics, tb structural genomics consortium, tbsgc, transcription regulator
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44923.18

構造登録者

Gao, C.,Bunker, R.D.,ten Bokum, A.,Kendall, S.L.,Stoker, N.G.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (登録日: 2010-04-21, 公開日: 2011-04-27, 最終更新日: 2023-11-01)

• 主引用文献: Ho, N.A.,Dawes, S.S.,Crowe, A.M.,Casabon, I.,Gao, C.,Kendall, S.L.,Baker, E.N.,Eltis, L.D.,Lott, J.S.; The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.; J. Biol. Chem., 291:7256-7266, 2016; PubMed: 26858250; DOI: 10.1074/jbc.M115.707760

実験手法

X-RAY DIFFRACTION (1.8 Å)