3MNE
Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by F608S mutation at 1.96A
Summary for 3MNE
Entry DOI | 10.2210/pdb3mne/pdb |
Descriptor | Glucocorticoid receptor, Nuclear receptor coactivator 2 peptide, GLYCEROL, ... (5 entities in total) |
Functional Keywords | protein-ligand complex, steroid nuclear receptor, mouse, agonist, co-activator, hormone receptor |
Biological source | Mus musculus (mouse) More |
Cellular location | Cytoplasm: P06537 Nucleus: Q61026 |
Total number of polymer chains | 2 |
Total formula weight | 32266.58 |
Authors | Schoch, G.A.,Seitz, T.,Benz, J.,Banner, D.,Stihle, M.,D'Arcy, B.,Thoma, R.,Sterner, R.,Hennig, M.,Ruf, A. (deposition date: 2010-04-21, release date: 2010-09-15, Last modification date: 2023-09-06) |
Primary citation | Seitz, T.,Thoma, R.,Schoch, G.A.,Stihle, M.,Benz, J.,D'Arcy, B.,Wiget, A.,Ruf, A.,Hennig, M.,Sterner, R. Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403:562-577, 2010 Cited by PubMed: 20850457DOI: 10.1016/j.jmb.2010.08.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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