3MLX
Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with an MN V3 peptide
Summary for 3MLX
Entry DOI | 10.2210/pdb3mlx/pdb |
Related | 3MLR 3MLS 3MLT 3MLU 3MLV 3MLW 3MLY 3MLZ |
Descriptor | Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain, HIV-1 gp120 third variable region (V3) crown, ... (4 entities in total) |
Functional Keywords | human monoclonal antibody, fab, hiv-1, gp120, third variable loop, antibody-antigen interaction, immune system |
Biological source | Homo sapiens More |
Cellular location | Surface protein gp120: Virion membrane ; Peripheral membrane protein . Transmembrane protein gp41: Virion membrane ; Single-pass type I membrane protein : P05877 |
Total number of polymer chains | 6 |
Total formula weight | 98581.92 |
Authors | Kong, X.-P. (deposition date: 2010-04-18, release date: 2010-07-14, Last modification date: 2017-11-08) |
Primary citation | Jiang, X.,Burke, V.,Totrov, M.,Williams, C.,Cardozo, T.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Conserved structural elements in the V3 crown of HIV-1 gp120. Nat.Struct.Mol.Biol., 17:955-961, 2010 Cited by PubMed: 20622876DOI: 10.1038/nsmb.1861 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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