3MK6
Substrate and Inhibitor Binding to Pank
Summary for 3MK6
Entry DOI | 10.2210/pdb3mk6/pdb |
Related | 2I7P |
Descriptor | Pantothenate kinase 3, ACETYL COENZYME *A, GLYCEROL, ... (4 entities in total) |
Functional Keywords | pank, inhibitor, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q9H999 |
Total number of polymer chains | 4 |
Total formula weight | 170620.35 |
Authors | Yun, M.-K.,White, S.W. (deposition date: 2010-04-14, release date: 2010-09-15, Last modification date: 2023-09-06) |
Primary citation | Leonardi, R.,Zhang, Y.M.,Yun, M.K.,Zhou, R.,Zeng, F.Y.,Lin, W.,Cui, J.,Chen, T.,Rock, C.O.,White, S.W.,Jackowski, S. Modulation of Pantothenate Kinase 3 Activity by Small Molecules that Interact with the Substrate/Allosteric Regulatory Domain. Chem.Biol., 17:892-902, 2010 Cited by PubMed: 20797618DOI: 10.1016/j.chembiol.2010.06.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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