3MIW

Crystal Structure of Rotavirus NSP4

Summary for 3MIW

• Entry DOI: 10.2210/pdb3miw/pdb
• Related: 2o1j 2o1k
• Descriptor: Non-structural glycoprotein 4, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: rotavirus enterotoxin, non structural protein, nsp4, pentameric coiled coil, virulence, viral protein
• Biological source: Human rotavirus G4 (RV-A)
• Cellular location: Non-structural glycoprotein 4: Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein (By similarity): Q82035
• Total number of polymer chains: 10
• Total formula weight: 66733.24

Authors

Chacko, A.R.,Read, R.J.,Dodson, E.J.,Rao, D.C.,Suguna, K. (deposition date: 2010-04-12, release date: 2011-05-25, Last modification date: 2024-02-21)

• Primary citation: Chacko, A.R.,Jeyakanthan, J.,Ueno, G.,Sekar, K.,Rao, C.D.,Dodson, E.J.,Suguna, K.,Read, R.J.; A new pentameric structure of rotavirus NSP4 revealed by molecular replacement.; Acta Crystallogr.,Sect.D, 68:57-61, 2012; PubMed: 22194333; DOI: 10.1107/S0907444911049705

Experimental method

X-RAY DIFFRACTION (2.5 Å)