3MIJ

Crystal structure of a telomeric RNA G-quadruplex complexed with an acridine-based ligand.

Summary for 3MIJ

• Entry DOI: 10.2210/pdb3mij/pdb
• Descriptor: RNA (5'-R(*UP*AP*GP*GP*GP*UP*UP*AP*GP*GP*GP*U)-3'), POTASSIUM ION, N,N'-[acridine-3,6-diylbis(1H-1,2,3-triazole-1,4-diylbenzene-3,1-diyl)]bis[3-(diethylamino)propanamide], ... (4 entities in total)
• Functional Keywords: quadruplex, rna-ligand complex, rna, telomeric
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 4737.45

Authors

Collie, G.W.,Neidle, S.,Parkinson, G.N. (deposition date: 2010-04-10, release date: 2011-02-16, Last modification date: 2023-09-06)

• Primary citation: Collie, G.W.,Sparapani, S.,Parkinson, G.N.,Neidle, S.; Structural basis of telomeric RNA quadruplex-acridine ligand recognition.; J.Am.Chem.Soc., 133:2721-2728, 2011; PubMed: 21291211; DOI: 10.1021/ja109767y

Experimental method

X-RAY DIFFRACTION (2.6 Å)