3MIB

Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound nitrite

Summary for 3MIB

• Entry DOI: 10.2210/pdb3mib/pdb
• Related: 1PHM 3MIC 3MID 3MIE 3MIF 3MIG 3MIH 3MLJ 3MLK 3MLL
• Descriptor: Peptidyl-glycine alpha-amidating monooxygenase, COPPER (II) ION, NICKEL (II) ION, ... (6 entities in total)
• Functional Keywords: oxidoreductase, monooxygenase, bioactive peptide activation, ascorbate
• Biological source: Rattus norvegicus (rat)
• Cellular location: Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein: P14925
• Total number of polymer chains: 1
• Total formula weight: 35608.21

Authors

Chufan, E.E.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. (deposition date: 2010-04-10, release date: 2010-11-24, Last modification date: 2023-09-06)

• Primary citation: Chufan, E.E.,Prigge, S.T.,Siebert, X.,Eipper, B.A.,Mains, R.E.,Amzel, L.M.; Differential Reactivity Between the Two Copper Sites of Peptidylglycine alpha-Hydroxylating Monooxygenase (PHM); J.Am.Chem.Soc., 132:15565-15572, 2010; PubMed: 20958070; DOI: 10.1021/ja103117r

Experimental method

X-RAY DIFFRACTION (2.35 Å)